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Cat No. | Product Name | Synonyms | Targets |
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T63790 | Cbl-b-IN-3 | E1/E2/E3 Enzyme | |
Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n... | |||
T26367 | Reltecimod | NSC-37096,P2TA,AB-103,AB103,P-2TA | |
Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection. | |||
T26367L | Reltecimod sodium | AB 103 sodium,AB-103 sodium,AB103 sodium | |
Reltecimod sodium, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00103 | CD28 Protein, Human/Cynomolgus, Recombinant (His) | Human,Cynomolgus | HEK293 Cells |
CD28 Protein, Human/Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is P10747. | |||
TMPK-00110 | CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) | Human,Cynomolgus,Rhesus | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting... | |||
TMPK-01176 | CD28 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting... | |||
TMPK-01177 | CD28 Protein, Canine, Recombinant (mFc) | Canine | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting... | |||
TMPK-00111 | CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated | Human,Cynomolgus,Rhesus | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting... | |||
TMPJ-00102 | CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated | Human,Cynomolyus | HEK293 Cells |
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is P10747. | |||
TMPJ-00099 | CD28 Protein, Mouse, Recombinant (hFc & His) | Mouse | HEK293 Cells |
T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the recep... | |||
TMPJ-00630 | B7-1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and... | |||
TMPJ-00958 | B7-1 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep... | |||
TMPJ-00420 | CTLA-4 Protein, Mouse, Recombinant (Flag) | Mouse | HEK293 Cells |
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory pro... | |||
TMPK-00166 | PD-L2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine pr... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-01290 | PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) | Cynomolgus | HEK293 Cells |
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine pr... | |||
TMPK-01066 | BTLA Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates anti... | |||
TMPK-00653 | B7-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00530 | BTLA Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates anti... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... |